This study systematically benchmarks different data augmentation setups across YOLO26 model size variants to determine the most effective setup for adenovirus detection in TEM images. The benchmarked setups include NAS, GAS, GMAS and DAS, all evaluated under identical training conditions.

The adenovirus dataset, selected from the published TEM virus dataset, was re-annotated by leveraging adenovirus particle positions to generate YOLO-compatible bounding box annotations. The experimental results demonstrated the impact of the benchmarked data augmentation setups on adenovirus detection with YOLO26 and indicated the most effective data augmentation setup.